InVivoMAb anti-mouse TIM-3 (CD366)

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Hsu JM et al., 2018 May 15, Nat Commun

Microglia activity modulated by T cell Ig and mucin domain protein 3 (Tim-3). Wang HW et al., 2015 Jan, Cell Immunol

Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. Hou H et al., 2014, PLoS One

Requirement for interactions of natural killer T cells and myeloid-derived suppressor cells for transplantation tolerance. Hongo D et al., 2014 Nov, Am J Transplant

TIM-3 regulates innate immune cells to induce fetomaternal tolerance. Chabtini L et al., 2013 Jan 1, J Immunol

Interactions between NKT cells and Tregs are required for tolerance to combined bone marrow and organ transplants. Hongo D et al., 2012 Feb 9, Blood

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells. Wang F et al., 2009, Immunobiology

TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Nakae S et al., 2007 Oct 1, Blood

Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity. Frisancho-Kiss S et al., 2006 Jun 1, J Immunol

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Monney L et al., 2002 Jan 31, Nature