InVivoPlus anti-mouse 4-1BB (CD137)

Catalog number: BP0169_100mg
Brand: Bio X Cell
Packing: 100 mg
Other sizes: Other sizes available
Price: € 4062.00
Expected delivery time: 7 days

Product specifications for - InVivoPlus anti-mouse 4-1BB (CD137)

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Product group: Antibodies
Category: Primary Antibodies
Application: Other Application
Host: Rat
Clonality: Monoclonal
Isotype: IgG2a
Molecular weight: 150 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 2-10 mg/ml
Scientific information: 
Clone ID: LOB12.3
Related products: 
Related products: Recommended Isotype Control(s): InVivoPlus rat IgG2a isotype control (BP0089)
Recommended Dilution Buffer: InVivoPure pH 8.0 Dilution Buffer (IP0080)
Additional information: 
Synonyms: LOB12.3; BP0169; BioXCell
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Dai M, Yip YY, Hellstrom I, Hellstrom KE. Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies. Clin Cancer Res. 2015;21(5):1127-38. Read more
Murphy JT, Burey AP, Beebe AM, et al. Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice. Blood. 2014;123(14):2172-80. Read more
Wei H, Zhao L, Li W, et al. Combinatorial PD-1 blockade and CD137 activation has therapeutic efficacy in murine cancer models and synergizes with cisplatin. PLoS ONE. 2013;8(12):e84927. Read more
Guo Z, Cheng D, Xia Z, et al. Combined TIM-3 blockade and CD137 activation affords the long-term protection in a murine model of ovarian cancer. J Transl Med. 2013;11:215. Read more
Dai M, Wei H, Yip YY, et al. Long-lasting complete regression of established mouse tumors by counteracting Th2 inflammation. J Immunother. 2013;36(4):248-57. Read more
Manzke N, Akhmetzyanova I, Hasenkrug KJ, Trilling M, Zelinskyy G, Dittmer U. CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells. J Virol. 2013;87(11):6306-13. Read more
Kwong B, Gai SA, Elkhader J, Wittrup KD, Irvine DJ. Localized immunotherapy via liposome-anchored Anti-CD137 + IL-2 prevents lethal toxicity and elicits local and systemic antitumor immunity. Cancer Res. 2013;73(5):1547-58. Read more
Curran MA, Kim M, Montalvo W, Al-shamkhani A, Allison JP. Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production. PLoS ONE. 2011;6(4):e19499. Read more
Taraban VY, Rowley TF, O'brien L, et al. Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses. Eur J Immunol. 2002;32(12):3617-27. Read more