Tech support
Shopping Cart
Login
Register
Forgot Password?
Products
Diagnostics
Suppliers
About us
Contact
+31 (0)26 326 4450
Find the product you need
Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
[KO Validated] beta-catenin Rabbit mAb
Catalog number:
A19657_200ul
Brand:
ABClonal
Packing:
200 ul
Other sizes:
Other sizes available
Price:
€ 734.00
Expected delivery time:
12 days
Quantity:
Spin Up
Spin Down
General
Product specifications for - [KO Validated] beta-catenin Rabbit mAb
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Properties:
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Storage instructions:
Store at -20-¦C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Scientific information:
Scientific info:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Additional information:
Synonyms:
RabMabs; Cancer Cell Proliferation; Cell Adhesion; EMT Research