NRF2 antibody [N2C2], Internal - Comparison, Orthogonal, Overexpression Validated

Catalog number: GTX103322_100ul
Brand: GeneTex
Packing: 100 ul
Other sizes: Other size available
Price: € 395.00
Expected delivery time: 10 days
Quantity:
GTX103322 ChIP assay Image
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GTX103322 IHC-P Image
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GTX103322 IP Image
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GTX103322 ICC/IF Image
GTX103322 ICC/IF Image...
GTX103322 ICC/IF Image
GTX103322 IP Image...
GTX103322 WB Image
GTX103322 ChIP assay Image...
GTX103322 WB Image
GTX103322 WB Image...
GTX103322 WB Image
GTX103322 WB Image...
GTX103322 WB Image
GTX103322 WB Image...
GTX103322 WB Image
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Product specifications for - NRF2 antibody [N2C2], Internal - Comparison, Orthogonal, Overexpression Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ChIP Chromatin ImmunoPrecipitation; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Species: Avian, Human, Mouse, Plant, Rat, Reptile, Zebra Fish
Host: Rabbit
Target: NFE2L2
Target description: nuclear factor, erythroid 2 like 2
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Controle: C8D30 , 3xFlag-human NFE2L2-transfected 293T , MDA-MB-231 nuclear extract , MDA-MB-231 nuclear extract (30uM tBHQ, 4hr) , HepG2 (10 microM MG132 treatment for 15 hr)
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.49 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]
Gene ID: 4780
Swiss prot ID: Q16236
Additional information: 
Synonyms: GTX_citation; GTX103322; HEBP1; IMDDHH; NRF2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; Nuclear factor, erythroid derived 2, like 2
A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, Oncogene Read more
A mitohormetic response to pro-oxidant exposure in the house mouse. Zhang Y et al., 2018 Jan 1, Am J Physiol Regul Integr Comp Physiol Read more
A new copper ionophore DPMQ protects cells against ultraviolet B irradiation by inhibiting the TRPV1 channel. Huang KF et al., 2018 Dec, J Cell Physiol Read more
Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model. Draheim T et al., 2016 Dec, Glia Read more
Andrographolide exerts anti-hepatitis C virus activity by up-regulating haeme oxygenase-1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells. Lee JC et al., 2014 Jan, Br J Pharmacol Read more
Antiviral effect of 7-(4-benzimidazole-butoxy)-coumarin on rhabdoviral clearance via Nrf2 activation regulated by PKCalpha/beta phosphorylation. Liu L et al., 2018 Dec, Fish Shellfish Immunol Read more
Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk. Cai J et al., 2018 Nov 13, Cell Rep Read more
Bone marrow-derived mesenchymal stem cells ameliorate liver injury in a rat model of sepsis by activating Nrf2 signaling. Selim SA et al., 2019 Mar, Histochem Cell Biol Read more
Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells. Tseng CK et al., 2017 Oct, Antiviral Res Read more
Celastrol prevents circulatory failure via induction of heme oxygenase-1 and heat shock protein 70 in endotoxemic rats. Wang YL et al., 2015 Mar 13, J Ethnopharmacol Read more