NRF2 antibody [N2C2], Internal
GTX103322
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Human, Mouse, Plant, Reptile, Rat, Zebra Fish
TargetNFE2L2
Overview
- SupplierGeneTex
- Product NameNRF2 antibody [N2C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.31 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4780
- Target nameNFE2L2
- Target descriptionnuclear factor, erythroid 2 like 2
- Target synonymsHEBP1; IMDDHH; NRF2; Nrf-2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2
- HostRabbit
- IsotypeIgG
- Protein IDQ16236
- Protein NameNuclear factor erythroid 2-related factor 2
- Scientific DescriptionNFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]
- ReactivityAvian, Human, Mouse, Plant, Reptile, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte. Wang SH et al., 2022 Sep 5, Antioxidants (Basel)Read more
- Gut Microbiota Mediates the Susceptibility of Mice to Sepsis-Associated Encephalopathy by Butyric Acid. Zhang H et al., 2022, J Inflamm ResRead more
- NOX4 regulates TGFbeta-induced proliferation and self-renewal in glioblastoma stem cells. Garcia-Gomez P et al., 2022 May, Mol OncolRead more
- Xanthohumol Protects the Rat Myocardium against Ischemia/Reperfusion Injury-Induced Ferroptosis. Lin JH et al., 2022, Oxid Med Cell LongevRead more
- Activation of alpha7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 Pathway. Cao K et al., 2022 Jan 4, Med Sci MonitRead more
- Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming. She H et al., 2021, J Inflamm ResRead more
- Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis. Liu Y et al., 2021, Front PharmacolRead more
- Gossypol Acetic Acid Attenuates Cardiac Ischemia/Reperfusion Injury in Rats via an Antiferroptotic Mechanism. Lin JH et al., 2021 Nov 10, BiomoleculesRead more
- Protective effect of sargahydroquinoic acid against Abeta25-35-evoked damage via PI3K/Akt mediated Nrf2 antioxidant defense system. Yoon JH et al., 2021 Dec, Biomed PharmacotherRead more
- Pre- and Early Post-treatment With Arthrospira platensis (Spirulina) Extract Impedes Lipopolysaccharide-triggered Neuroinflammation in Microglia. Piovan A et al., 2021, Front PharmacolRead more