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GTX70216 IHC-P Image
GTX70216 IHC-P Image
GTX70216 IHC-P Image

p53 antibody [Pab1801] - Orthogonal Validated

Research Use Only
GTX70216
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    p53 antibody [Pab1801] - Orthogonal Validated
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Pab1801
  • Concentration
    1 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer. Yamamura S et al., 2010 Jun, Mol Cancer Ther
    Read more
  • Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/beta-Catenin Signaling Pathway in Glioma Cells. Chu CW et al., 2019 Jan 22, Int J Mol Sci
    Read more