PD-L1 antibody [HL1056] - Comparison, Orthogonal Validated

Catalog number: GTX636033_100ul
Brand: GeneTex
Packing: 100 ul
Other sizes: Other size available
Price: € 413.00
Expected delivery time: 10 days
Quantity:
Various whole cell extracts (30 mic...

Product specifications for - PD-L1 antibody [HL1056] - Comparison, Orthogonal Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: Western Blot
Species: Human
Host: Rabbit
Target: CD274
Target description: CD274 molecule
Clonality: Monoclonal
Conjugation: Unconjugated
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Clone ID: HL1056
Gene ID: 29126
Swiss prot ID: Q9NZQ7
Additional information: 
Synonyms: GTX636033; B7 homolog 1; B7-H; B7H1; CD274 antigen; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; programmed cell death 1 ligand 1