Various whole cell extracts (30 microg) were separated by 10% SDS-PAGE, and the membranes were blotted with PD-L1 antibody [HL1056] (GTX636033) diluted at 1:1000 and competitors antibody diluted at 1:200. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. *The competitor is not affiliated with GeneTex and does not endorse this product.
PD-L1 antibody [HL1056]
GTX636033
Product group Antibodies
Overview
- SupplierGeneTex
- Product NamePD-L1 antibody [HL1056]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDHL1056
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203