PD-L1 antibody - KO/KD, Comparison, Orthogonal, Overexpression Validated

Catalog number: GTX104763_100ul
Brand: GeneTex
Packing: 100 ul
Other sizes: Other size available
Price: € 395.00
Expected delivery time: 10 days
Quantity:
GTX104763 WB Image
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GTX104763 IHC-P Image
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GTX104763 ICC/IF Image
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GTX104763 IHC-P Image
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GTX104763 IHC-P Image
GTX104763 WB Image...
GTX104763 WB Image
GTX104763 IHC-P Image...
GTX104763 WB Image
GTX104763 IHC-P Image...
GTX104763 WB Image
GTX104763 IHC-P Image...
GTX104763 WB Image
GTX104763 WB Image...
GTX104763 WB Image
GTX104763 WB Image...

Product specifications for - PD-L1 antibody - KO/KD, Comparison, Orthogonal, Overexpression Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Frozen; ImmunoHistoChemistry Parrafin; Western Blot
Species: Human
Host: Rabbit
Target: CD274
Target description: CD274 molecule
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.9 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Gene ID: 29126
Swiss prot ID: Q9NZQ7
Additional information: 
Synonyms: GTX_citation; GTX104763; B7 homolog 1; B7-H; B7H1; CD274 antigen; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; programmed cell death 1 ligand 1
A combination of anti-PD-L1 mAb plus Lm-LLO-E6 vaccine efficiently suppresses tumor growth and metastasis in HPV-infected cancers. Lin PL et al., 2017 Sep, Cancer Med Read more
An increase in BAG-1 by PD-L1 confers resistance to tyrosine kinase inhibitor in non-small cell lung cancer via persistent activation of ERK signalling. Lin PL et al., 2017 Nov, Eur J Cancer Read more
Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Li CW et al., 2018 Feb 12, Cancer Cell Read more
High PD-L1 Expression Correlates with Metastasis and Poor Prognosis in Oral Squamous Cell Carcinoma. Lin YM et al., 2015, PLoS One Read more
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. Chan LC et al., 2019 Jul 15, J Clin Invest Read more
Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. Wang LT et al., 2017 Aug 1, Cancer Res Read more
Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Cha JH et al., 2018 Aug 16, Mol Cell Read more
Nuclear localization of PD-L1: artifact or reality? Polioudaki H et al., 2019 Apr, Cell Oncol (Dordr) Read more
Overexpressed miR-195 attenuated immune escape of diffuse large B-cell lymphoma by targeting PD-L1. He B et al., 2018 Feb, Biomed Pharmacother Read more
Soluble PD-L1 with PD-1-binding capacity exists in the plasma of patients with non-small cell lung cancer. Takeuchi M et al., 2018 Apr, Immunol Lett Read more