PD-L1 antibody
GTX104763
Overview
- SupplierGeneTex
- Product NamePD-L1 antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody is specific for human PDL1 protein, and it does not cross react with human PDL2 protein.
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration0.97 mg/ml
- FormulationLiquid
- Gene ID29126
- Target nameCD274
- Target descriptionCD274 molecule
- Target synonymsB7 homolog 1; B7-H; B7H1; CD274 antigen; hPD-L1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; programmed cell death 1 ligand 1
- Protein IDQ9NZQ7
- Protein NameProgrammed cell death 1 ligand 1
- Scientific DescriptionInvolved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Semaphorin 4C promotes motility and immunosuppressive activity of cancer cells via CRMP3 and PD-L1. Hung YH et al., 2022, Am J Cancer ResRead more
- Programme death ligand 1 expressions as a surrogate for determining immunotherapy in cervical carcinoma patients. Omenai SA et al., 2022, PLoS OneRead more
- miR-4759 suppresses breast cancer through immune checkpoint blockade. Lin YZ et al., 2022, Comput Struct Biotechnol JRead more
- Expression of programmed cell death ligand-1 protein in germinal center B-cell-like and non-germinal center B-cell-like subtypes of diffuse large B-cell lymphoma. Asrini R et al., 2022 Feb, Mol Clin OncolRead more
- Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer. Li L et al., 2021 May, Cancer SciRead more
- The PD-L1 metabolic interactome intersects with choline metabolism and inflammation. Pacheco-Torres J et al., 2021 Feb 19, Cancer MetabRead more
- PD-L1 as a prognostic biomarker in surgically resectable non-small cell lung cancer: a meta-analysis. Tuminello S et al., 2020 Aug, Transl Lung Cancer ResRead more
- The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer. Chou CW et al., 2020, Am J Cancer ResRead more
- NDAT Targets PI3K-Mediated PD-L1 Upregulation to Reduce Proliferation in Gefitinib-Resistant Colorectal Cancer. Huang TY et al., 2020 Aug 3, CellsRead more
- Differential Expression and Clinicopathological Significance of HER2, Indoleamine 2,3-Dioxygenase and PD-L1 in Urothelial Carcinoma of the Bladder. Kim D et al., 2020 Apr 27, J Clin MedRead more