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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
Perforin Rabbit pAb
Catalog number:
A0093_50ul
Brand:
ABClonal
Packing:
50 ul
Other sizes:
Other sizes available
Price:
€ 203.00
Expected delivery time:
12 days
Quantity:
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General
Product specifications for - Perforin Rabbit pAb
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Properties:
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Storage instructions:
Store at -20-¦C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Scientific information:
Scientific info:
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
Additional information:
Synonyms:
A0093