Rabbit anti-human NLRP2 polyclonal Antibody

Catalog number: MBS1495184_0,05ml
Brand: MyBioSource
Packing: 0,05 ml
Price: € 180.00
Expected delivery time: 21 days
Immunohistochemistry of paraffin-em...
Immunohistochemistry of paraffin-em...

Product specifications for - Rabbit anti-human NLRP2 polyclonal Antibody

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; ImmunoHistoChemistry
Species: Human
Host: Rabbit
Target: NLRP2
Target description: NLR family pyrin domain containing 2
Clonality: Polyclonal
Isotype: IgG
Purity: Antigen Affinity Purified
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: -20-¦C or -80-¦C
Scientific information: 
Scientific info: Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Gene ID: 55655
Swiss prot ID: Q9NX02
Additional information: 
Synonyms: CLR19.9; NACHT, leucine rich repeat and PYD containing 2; NACHT, LRR and PYD domains-containing protein 2; NALP2; NBS1; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2; nucleotide-binding site protein 1; PAN1; PYPAF2; PYRIN domain and NACHT domain-containing protein 1; PYRIN-containing APAF1-like protein 2