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GTX114210 WB Image
GTX114210 WB Image
GTX114210 WB Image

TDP43 antibody

Research Use Only
GTX114210
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    TDP43 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.18 mg/ml
  • Isotype
    IgG
  • Scientific Description
    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP. Majumder P et al., 2016 Nov, Acta Neuropathol
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  • Metabolism and mis-metabolism of the neuropathological signature protein TDP-43. Huang CC et al., 2014 Jul 15, J Cell Sci
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  • Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol Cell
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  • TDP-43 Regulates Coupled Dendritic mRNA Transport-Translation Processes in Co-operation with FMRP and Staufen1. Chu JF et al., 2019 Dec 3, Cell Rep
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  • Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons. Wu LS et al., 2019 Mar 29, Acta Neuropathol Commun
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