Overview
- SupplierGeneTex
- Product NameTNF alpha antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.04 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Adipocytes initiate an adipose-cerebral-peripheral sympathetic reflex to induce insulin resistance during high-fat feeding. Cao W et al., 2019 Sep 13, Clin Sci (Lond)Read more
- Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase. Chiang MH et al., 2017, Front PharmacolRead more
- Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo. Lam HYP et al., 2021 Jun, PLoS Negl Trop DisRead more
- Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype. Zhou Y et al., 2020 Dec, Oncol LettRead more
- Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype. Zhou Y et al., 2020 Dec, Oncol LettRead more
- Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement. Chen YC et al., 2017 Sep, J Formos Med AssocRead more
- Apoptosis perturbations and expression of regulatory inflammatory factors in cisplatin-depleted rat livers under l-arginine protection. El-Sayed RM et al., 2019 May, Can J Physiol PharmacolRead more
- Bisperoxovanadium induces M2-type macrophages and promotes functional recovery after spinal cord injury. Liu J et al., 2019 Dec, Mol ImmunolRead more
- Brain-to-cervical lymph node signaling after stroke. Esposito E et al., 2019 Nov 22, Nat CommunRead more