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TSG101 antibody [4A10] - KO/KD, Orthogonal Validated

Catalog number: GTX70255100
Brand: GeneTex
Packing: 100 ul
Price: € 490.00
Expected delivery time: 10 days
Quantity:
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GTX70255 ELISA Image
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GTX70255 WB Image
GTX70255 WB Image...
GTX70255 WB Image
GTX70255 WB Image...
GTX70255 IHC-P Image
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GTX70255 IHC-P Image
GTX70255 WB Image...
GTX70255 IHC-P Image
GTX70255 WB Image...
GTX70255 WB Image
GTX70255 WB Image...
GTX70255 WB Image
GTX70255 IHC-P Image...
GTX70255 WB Image
GTX70255 IHC-P Image...
GTX70255 WB Image...

Product specifications for - TSG101 antibody [4A10] - KO/KD, Orthogonal Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: Electron Microscopy; ELISA; Flow Cytometry; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Host: Mouse
Target: TSG101
Target description: tumor susceptibility 101
Clonality: Monoclonal
Isotype: IgG1
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1.8 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: TSG101-4A10 recognizes TSG101 protein, the product of a recently identified Tumor Susceptibility Gene whose inactivation in mouse fibroblasts results in cell transformation and the ability of those cells to form tumors in nude mice. The TSG101 gene encodes a 46 kDa protein and contains a proline-rich domain and a luecine-zipper motif within a coiled-coil domain near the carboxyl terminus.
Clone ID: 4A10
Gene ID: 7251
Swiss prot ID: Q99816
Additional information: 
Synonyms: GTX_citation; GTX70255; ESCRT-I complex subunit TSG101; TSG10; tumor susceptibility gene 10; tumor susceptibility gene 101; tumor susceptibility gene 101 protein; tumor susceptibility protein; VPS23
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Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules. Boussadia Z et al., 2018 Oct 5, J Exp Clin Cancer Res Read more
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Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid beta (Abeta) production in the trans-Golgi network. Choy RW et al., 2012 Jul 24, Proc Natl Acad Sci U S A Read more
An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins. Gullapalli A et al., 2006 Mar, Mol Biol Cell Read more
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. Colombo M et al., 2013 Dec 15, J Cell Sci Read more
Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. Chiou CT et al., 2003 Oct, J Gen Virol Read more
Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Guo H et al., 2017 Dec 18, Dev Cell Read more
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