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GTX113574 WB Image
GTX113574 WB Image
GTX113574 WB Image

VEGFC antibody

Research Use Only
GTX113574
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    VEGFC antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.93 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination. Wang CA et al., 2020, J Extracell Vesicles
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  • High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells. Huang YL et al., 2018, Cell Physiol Biochem
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  • Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Zhang J et al., 2021 Apr 29, Ecotoxicol Environ Saf
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  • Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells. Huang YH et al., 2016, PLoS One
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  • LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Lin YC et al., 2018 Oct, Biochim Biophys Acta Mol Cell Biol Lipids
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  • Temporal expression and localization of vascular endothelial growth factor family members in the bovine uterus during peri-implantation period. Hayashi KG et al., 2019 Jul 15, Theriogenology
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  • The significance of SMARCB1 in the pathogenesis of renal cell carcinoma with rhabdoid features. Wang YW et al., 2021 Oct, Transl Oncol
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