Overview
- SupplierGeneTex
- Product NameVEGFC antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.93 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination. Wang CA et al., 2020, J Extracell VesiclesRead more
- High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells. Huang YL et al., 2018, Cell Physiol BiochemRead more
- Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Zhang J et al., 2021 Apr 29, Ecotoxicol Environ SafRead more
- Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells. Huang YH et al., 2016, PLoS OneRead more
- LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Lin YC et al., 2018 Oct, Biochim Biophys Acta Mol Cell Biol LipidsRead more
- Temporal expression and localization of vascular endothelial growth factor family members in the bovine uterus during peri-implantation period. Hayashi KG et al., 2019 Jul 15, TheriogenologyRead more
- The significance of SMARCB1 in the pathogenesis of renal cell carcinoma with rhabdoid features. Wang YW et al., 2021 Oct, Transl OncolRead more