Bio-Connect

ZO-1 antibody [HL1133]

GTX636399
GeneTex
TargetTJP1
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    ZO-1 antibody [HL1133]
  • Delivery Days Customer
    9
  • Antibody Specificity
    We do not recommend use of this product for Mouse,Rat.
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Clone ID
    HL1133
  • Concentration
    2 mg/ml
  • Formulation
    Liquid
  • Gene ID7082
  • Target name
    TJP1
  • Target description
    tight junction protein 1
  • Target synonyms
    tight junction protein ZO-1; ZO-1; zona occludens 1; zonula occludens 1 protein
  • Protein IDQ07157
  • Protein Name
    Tight junction protein ZO-1
  • Scientific Description
    This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203