Anticancer agent 65 [2407861-48-5]

MedChem Express

Anticancer agent 65 [2407861-48-5]

10

2407861-48-5

Research Use Only

C36H63NO5

589.89

Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 microM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells[1].

C[C@]12[C@]3([C@@]([C@@H](C[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)OC(C5CCNCC5)=O)C)([H])CC2)C)O)([H])[C@@](CC3)([H])[C@](C)(O)CCCC(C)(O)C)C

12131703