Antihistamine-1

MedChem Express

Antihistamine-1 [1186430-60-3]

10

1186430-60-3

Research Use Only

99.45

C23H24FN5

389.47

Antihistamine-1 is a H1-antihistamine ( K i =6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC 50 s of 5.4 and 0.8 microM, respectively.

CC1=CN(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)N=C1

-20°C,2°C to 8°C

12352200