Bio-Connect

Antiproliferative agent-54

HY-135216
MedChem Express
Molecular Weight562.54
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Antiproliferative agent-54
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C29H25F3N6O3
  • Molecular Weight
    562.54
  • Scientific Description
    Antiproliferative agent-54 (Compound 6z) is the inhibitor for multiple kinases, such as ABL WT , B-RAF , EGFR , HCK , LYN A and SRC with IC 50 of 6-50 nM. Antiproliferative agent-54 inhibits proliferation of several cancer cell, inhibits HUVEC and HepG2, with EC 50 of 34 and 38 nM. Antiproliferative agent-54 exhibits good pharmacokinetic characteristics in rats [1] .
  • SMILES
    O=C(C1=CC2=CC(NCC3=CC(NC(C4=CC(C(F)(F)F)=CC(N5C=C(C)N=C5)=C4)=O)=CC=C3C)=CN=C2N1)OC
  • UNSPSC
    12352200