Antiproliferative agent-59
HY-168102
Molecular Weight410.46
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameAntiproliferative agent-59
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC26H22N2O3
- Molecular Weight410.46
- Scientific DescriptionAntiproliferative agent-59 (Compound 14u) is an inhibitor for tubulin polymerization. Antiproliferative agent-59 exhibits antiproliferative activities against cancer cells Huh7, SGC-7901, and MCF-7 with IC50 of 0.03, 0.18, and 0.13microM. Antiproliferative agent-59 arrests the cell cycle at G2/M phase and induces apoptosis in Huh7 cell. Antiproliferative agent-59 exhibits antitumor efficacy against liver cancer in Huh7 xenograft mouse models, without significant toxicity[1].
- SMILESCOC1=C(OC)C(OC)=CC(C2=CC=NC3=CC=C(C4=CC=CC5=C4C=CN5)C=C23)=C1
- UNSPSC12352200