Antiproliferative agent-60
HY-168113
Molecular Weight517.42
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameAntiproliferative agent-60
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC24H29BrN4O4
- Molecular Weight517.42
- Scientific DescriptionAntiproliferative agent-60 (compound 8c) is a 11-Azaartemisinin derivative with superior anticancer activities. Antiproliferative agent-60 shows IC50 values of 7.7 microM, 42.5 microM, and 15.5 microM for epidermoid carcinoma (KB), HepG2, and A549 cells, respectively. Antiproliferative agent-60 exhibits significant tumor selectivity, up to 32-fold higher compared to Hek293 normal cells[1].
- SMILESBrC1=CC=CC(N2C=C(CN3[C@H]4[C@]56C(CC[C@@H](C)C5CC[C@](OO6)(C)O4)[C@@H](C)C3=O)N=N2)=C1
- UNSPSC12352200