Antitrypanosomal agent 7
HY-147550
Molecular Weight480.43
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameAntitrypanosomal agent 7
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC23H31Cl2N5O2
- Molecular Weight480.43
- Scientific DescriptionAntitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei ( T. brucei ) than Nifurtimox, with an IC 50 value of 0.71 microM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA [1] .
- SMILESCOC1=CC(C2=NC3=CC(C4=NCCN4)=CC=C3N2)=CC=C1OCCN(CC)CC.[H]Cl.[H]Cl
- UNSPSC12352200