AOH1996

AbMole BioScience

AOH1996

9

2089314-64-5

Chemical

Research Use Only

C26H22N2O4

426.46

AOH1996 is an orally active small molecule PCNA inhibitor, which can be obtained by adding a methoxy group to the interstitial position of the benzene ring at the end of AOH1160, and enhances the interaction between PCNA and RPB1, the largest subunit of RNA polymerase II, as well as selectively kills cancer cells, which can be used in cancer-related research.

COC1=CC=CC(=C1)OC2=C(NC(=O)CNC(=O)C3=CC=CC4=C3C=CC=C4)C=CC=C2

12352200