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Western Blot analysis of Hela cell using APAF1 Polyclonal Antibody at dilution of 1:350
Western Blot analysis of Hela cell using APAF1 Polyclonal Antibody at dilution of 1:350
Western Blot analysis of Hela cell using APAF1 Polyclonal Antibody at dilution of 1:350

APAF1 Polyclonal Antibody

E-AB-12215
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    APAF1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.7mg/ml
  • Scientific Description
    This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
  • UNSPSC
    12352203