APC Anti-Human CD35 Antibody
RD20800F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetCR1
Overview
- SupplierReddot Biotech
- Product NameAPC Anti-Human CD35 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDE11
- ConjugateAPC (Allophycocyanin)
- Gene ID1378
- Target nameCR1
- Target descriptioncomplement C3b/C4b receptor 1 (Knops blood group)
- Target synonymsC3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); complement receptor 1; complement receptor type 1; KN; Knops blood group antigen
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203