APC Anti-Rat CD8a Antibody

Reddot Biotech

APC Anti-Rat CD8a Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

OX-8

APC (Allophycocyanin)

Cd8a

CD8a molecule

CD8 antigen 32 kDa chain; CD8 antigen, alpha-chain; OX-8 membrane antigen; T-cell surface glycoprotein CD8 alpha chain

Mouse

IgG1

CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8Oe+/-. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8beta chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 Oe+/-beta heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

Rat

2°C to 8°C

12352203