Bio-Connect

APEH Polyclonal Antibody

RD81429A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAPEH
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    APEH Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID327
  • Target name
    APEH
  • Target description
    acylaminoacyl-peptide hydrolase
  • Target synonyms
    AARE; ACPH; acylamino-acid-releasing enzyme; acylaminoacyl-peptidase; acyl-peptide hydrolase; APH; D3F15S2; D3S48E; DNF15S2; N-acylaminoacyl-peptide hydrolase; OPH; oxidized protein hydrolase
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203