APEH Polyclonal Antibody
RD81429A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAPEH
Overview
- SupplierReddot Biotech
- Product NameAPEH Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID327
- Target nameAPEH
- Target descriptionacylaminoacyl-peptide hydrolase
- Target synonymsAARE; ACPH; acylamino-acid-releasing enzyme; acylaminoacyl-peptidase; acyl-peptide hydrolase; APH; D3F15S2; D3S48E; DNF15S2; N-acylaminoacyl-peptide hydrolase; OPH; oxidized protein hydrolase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203