APEX1 Polyclonal Antibody

Reddot Biotech

APEX1 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

APEX1

apurinic/apyrimidinic endodeoxyribonuclease 1

AP endonuclease class I; AP lyase; APE; APE1; APEN; APEX; APEX nuclease (multifunctional DNA repair enzyme) 1; apurinic/apyrimidinic (abasic) endonuclease; apurinic-apyrimidinic endonuclease 1; APX; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; HAP1; protein REF-1; redox factor-1; REF1

Rabbit

IgG

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Human, Mouse, Rat

-20°C

12352203