Dasminapant [1570231-89-8]

MedChem Express

Dasminapant [1570231-89-8]

10

1570231-89-8

Research Use Only

99.36

C60H72N10O10S2

1157.40

Dasminapant (APG-1387), a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP-1, cIAP-2, and ML-IAP). Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma[1][2][3][4][5].

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-20°C

12352200