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Apicidin

Apicidin

T14305
TargetMol Chemicals
CAS Number183506-66-3
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Product group Chemicals
Molecular Weight623.78
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Apicidin
  • Delivery Days Customer
    14
  • CAS Number
    183506-66-3
  • Category Supplier
    Chemical
  • Chemical Name
    Apicidin
  • Molecular Formula
    C34H49N5O6
  • Molecular Weight
    623.78
  • Scientific Description
    Apicidin (OSI 2040) is a fungal metabolite, acts as a histone deacetylase (HDAC) inhibitor. It has antiparasitic activity and a broad spectrum antiproliferative activity[1].
  • Shelf life instruction
    3 years
  • SMILES
    C(C=1C=2C(N(OC)C1)=CC=CC2)[C@H]3C(=O)NC([C@H](CC)C)C(=O)N4[C@@](C(=O)N[C@@H](CCCCCC(CC)=O)C(=O)N3)(CCCC4)[H]
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Han JW, et al. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Cancer Res. 2000 Nov 1;60(21):6068-74.
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