APLP2 Polyclonal Antibody

Reddot Biotech

APLP2 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

APLP2

amyloid beta precursor like protein 2

amyloid beta (A4) precursor-like protein 2; amyloid precursor protein homolog HSD-2; amyloid-like protein 2; APLP-2; APPH; APPL2; CDEBP; CDEI box-binding protein; testicular tissue protein Li 23

Rabbit

IgG

This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimers disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Human, Mouse, Rat

-20°C

12352203