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CgoaEWY7MW6EGkDaAAAAAHLnbSQ177.png
CgoaEWY7MW6EGkDaAAAAAHLnbSQ177.png

APN-C3-NH-Boc

T14308
TargetMol Chemicals
CAS Number1539292-60-8
Product group Chemicals
Molecular Weight327.38
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Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    APN-C3-NH-Boc
  • Delivery Days Customer
    999
  • CAS Number
    1539292-60-8
  • Category Supplier
    Chemical
  • Chemical Name
    APN-C3-NH-Boc
  • Molecular Formula
    C18H21N3O3
  • Molecular Weight
    327.38
  • Scientific Description
    APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
  • Shelf life instruction
    3 years
  • SMILES
    N#CC#CC1=CC=C(C=C1)NC(=O)CCCNC(=O)OC(C)(C)C
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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