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ProductsBack/APN-C3-PEG4-alkyne [2183440-36-8]
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APN-C3-PEG4-alkyne [2183440-36-8]

Research Use Only
T14309
TargetMol Chemicals
CAS Number2183440-36-8
DownloadMSDS
Product group Chemicals
Molecular Weight469.53
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    APN-C3-PEG4-alkyne [2183440-36-8]
  • Delivery Days Customer
    16
  • CAS Number
    2183440-36-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    APN-C3-PEG4-alkyne
  • Molecular Formula
    C25H31N3O6
  • Molecular Weight
    469.53
  • Scientific Description
    APN-C3-PEG4-alkyne is a PEG-based linker for PROTACs, joining two essential ligands critical for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
  • Shelf life instruction
    3 years
  • SMILES
    N#CC#CC1=CC=C(C=C1)NC(=O)CCCNC(=O)CCOCCOCCOCCOCC#C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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