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APN-C3-PEG4-azide [2183440-32-4]

Research Use Only
T14310
TargetMol Chemicals
CAS Number2183440-32-4
Product group Chemicals
Molecular Weight500.55
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    APN-C3-PEG4-azide [2183440-32-4]
  • Delivery Days Customer
    14
  • CAS Number
    2183440-32-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    APN-C3-PEG4-azide
  • Molecular Formula
    C24H32N6O6
  • Molecular Weight
    500.55
  • Scientific Description
    APN-C3-PEG4-azide is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands vital for PROTAC molecule formation. This linker supports selective protein degradation via the cells ubiquitin-proteasome system.
  • Shelf life instruction
    3 years
  • SMILES
    N#CC#CC1=CC=C(C=C1)NC(=O)CCCNC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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