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APN-PEG4-DBCO

T17451
TargetMol Chemicals
Molecular Weight676.76
Product group Chemicals
Price on request
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More than 130 suppliers
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    APN-PEG4-DBCO
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Chemical Name
    APN-PEG4-DBCO
  • Molecular Formula
    C39H40N4O7
  • Molecular Weight
    676.76
  • Scientific Description
    APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), comprised of a four-unit PEG and a DBCO moiety. It finds application in the synthesis of ADCs[1].
  • Shelf life instruction
    3 years
  • SMILES
    O=C(CCC(NCCOCCOCCOCCOCCC(NC1=CC=C(C#CC#N)C=C1)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
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