Bio-Connect
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CgoaEGY7QFiEQ-nDAAAAAJKMwAA527.png
CgoaEGY7QFiEQ-nDAAAAAJKMwAA527.png

APN-PEG4-PFP

Research Use Only
T17452
TargetMol Chemicals
Molecular Weight584.49
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    APN-PEG4-PFP
  • Delivery Days Customer
    16
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    APN-PEG4-PFP
  • Molecular Formula
    C27H25F5N2O7
  • Molecular Weight
    584.49
  • Scientific Description
    APN-PEG4-PFP is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
  • Shelf life instruction
    3 years
  • SMILES
    FC1=C(OC(CCOCCOCCOCCOCCNC(C2=CC=C(C#CC#N)C=C2)=O)=O)C(F)=C(F)C(F)=C1F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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