Bio-Connect

Apolipoprotein A1 antibody

GTX112692
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAPOA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Apolipoprotein A1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.58 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID335
  • Target name
    APOA1
  • Target description
    apolipoprotein A1
  • Target synonyms
    apo(a); apo-AI; apolipoprotein A-I; epididymis secretory sperm binding protein; HPALP2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02647
  • Protein Name
    Apolipoprotein A-I
  • Scientific Description
    This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Secretion of mitochondrial DNA via exosomes promotes inflammation in Behcets syndrome.
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  • Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples. Karimi N et al., 2022 May, J Extracell Vesicles
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  • Synergy of Human Platelet-Derived Extracellular Vesicles with Secretome Proteins Promotes Regenerative Functions. Gomes FG et al., 2022 Jan 23, Biomedicines
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  • Characterization of surface markers on extracellular vesicles isolated from lymphatic exudate from patients with breast cancer. Ekstroem K et al., 2022 Jan 10, BMC Cancer
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  • Circulating oxidized LDL, increased in patients with acute myocardial infarction, is accompanied by heavily modified HDL. Sawada N et al., 2020 Jun, J Lipid Res
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  • Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma. Onodi Z et al., 2018, Front Physiol
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