Apolipoprotein B antibody
GTX40737
Overview
- SupplierGeneTex
- Product NameApolipoprotein B antibody
- Delivery Days Customer9
- Antibody SpecificityRecognizes mouse as well as human Apo B48 and B100 as these proteins are highly conserved.
- Application Supplier NoteWB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID238055
- Target nameApob
- Target descriptionapolipoprotein B
- Target synonymsAI315052; Apo B-100; apob-; apob-100; apob-48; apolipoprotein B-100
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100. Unlike the apoB-48 and apoB-100 structural equivalents in human, which are synthesized exclusively in the gut and liver, respectively, the mouse apoB-48 isoform is also found in mouse liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2179 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Generalized eruptive xanthoma with prominent deposition of naked chylomicrons: evidence for chylomicrons as the origin of urate-like crystals. Bito T et al., 2010 Nov, J Cutan PatholRead more