APRT Polyclonal Antibody

Reddot Biotech

APRT Polyclonal Antibody

5

Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

APRT

adenine phosphoribosyltransferase

adenine phosphoribosyltransferase; AMP; AMP diphosphorylase; AMP pyrophosphorylase; APRTD; transphosphoribosidase

Rabbit

IgG

Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C

12352203