Immunohistochemistry analysis of paraffin-embedded human Prostate using AR Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human Prostate using AR Polyclonal Antibody at dilution of 1:300.
AR Polyclonal Antibody
E-AB-70112
Product group Antibodies
Overview
- SupplierElabscience
- Product NameAR Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.
- UNSPSC12352203