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ProductsBack/Aranorosin [117184-53-9]
Chemical Structure
Chemical Structure
Chemical Structure

Aranorosin [117184-53-9]

Research Use Only
AG-CN2-0114
AdipoGen Life Sciences
CAS Number117184-53-9
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Product group Chemicals
Estimated Purity>95%
Molecular Weight419.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Aranorosin [117184-53-9]
  • Delivery Days Customer
    10
  • CAS Number
    117184-53-9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C23H33NO6
  • Molecular Weight
    419.5
  • Scientific Description
    Antibiotic [1, 2]. Antibacterial [1-6]. Antifungal [1-6]. Anticancer compound [3, 4]. Inhibits anti-apoptotic functions regulated by Bcl-2 [7]. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6)/APH(2) [8]. - Chemical. CAS: 117184-53-9. Formula: C23H33NO6. MW: 419.5. Isolated from Gymnascella sp. Antibiotic. Antibacterial. Antifungal. Anticancer compound. Inhibits anti-apoptotic functions regulated by Bcl-2. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6)/APH(2).
  • SMILES
    CCCCCC[C@H](C)\C=C(/C)\C=C\C(=O)N[C@@H]1C[C@]2(O[C@@H]1O)[C@H]1O[C@H]1C(=O)[C@H]1O[C@@H]21
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. I. Taxonomy, fermentation, isolation, chemical and biological properties: K. Roy, et al.; J. Antibiot. (Tokyo) 41, 1780 (1988)
  • Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. II. Structure elucidation: H.W. Fehlhaber, et al.; J. Antibiot. (Tokyo) 41, 1785 (1988)
  • Structure of aranorosin, a new antibiotic of a novel skeletal type: H.W. Fehlhaber, et al.; JACS 110, 8242 (1988)
  • Stereoselective synthesis of the functionalized spirocyclic core of aranorosin: P. Wipf & Y. Kim; J. Org. Chem. 58, 1649 (1993)
  • Structure of a model for the aranorosin nucleus: R. C. Haltiwanger, et al.; Acta Cryst. C 50, 274 (1994)
  • Structure-activity relationships of new aranorosin analogs to antifungal activity: E.K. Vijayakumar, et al.; J. Antibiot. (Tokyo) 51, 522 (1998)
  • Aranorosin and a novel derivative inhibit the anti-apoptotic functions regulated by Bcl-2: T. Nakashima, et al.; BBRC 377, 1085 (2008)
  • Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2''): T. Suga, et al.; J. Antibiot. (Tokyo) 65, 527 (2012)