Aranorosin [117184-53-9]

Name: Aranorosin [117184-53-9]
SKU: AG-CN2-0114_A27
Price: 178 EUR
Availability: BackOrder

AG-CN2-0114

CAS Number117184-53-9

Product group Chemicals

Estimated Purity>95%

Molecular Weight419.5

Overview

Supplier
AdipoGen Life Sciences
Product Name
Aranorosin [117184-53-9]
Delivery Days Customer
10
CAS Number
117184-53-9
Certification
Research Use Only
Estimated Purity
>95%
Hazard Information
Warning
Molecular Formula
C23H33NO6
Molecular Weight
419.5
Scientific Description
Antibiotic [1, 2]. Antibacterial [1-6]. Antifungal [1-6]. Anticancer compound [3, 4]. Inhibits anti-apoptotic functions regulated by Bcl-2 [7]. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6)/APH(2) [8]. - Chemical. CAS: 117184-53-9. Formula: C23H33NO6. MW: 419.5. Isolated from Gymnascella sp. Antibiotic. Antibacterial. Antifungal. Anticancer compound. Inhibits anti-apoptotic functions regulated by Bcl-2. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6)/APH(2).
SMILES
CCCCCC[C@H](C)\C=C(/C)\C=C\C(=O)N[C@@H]1C[C@]2(O[C@@H]1O)[C@H]1O[C@H]1C(=O)[C@H]1O[C@@H]21
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352200

Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. I. Taxonomy, fermentation, isolation, chemical and biological properties: K. Roy, et al.; J. Antibiot. (Tokyo) 41, 1780 (1988)
Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. II. Structure elucidation: H.W. Fehlhaber, et al.; J. Antibiot. (Tokyo) 41, 1785 (1988)
Structure of aranorosin, a new antibiotic of a novel skeletal type: H.W. Fehlhaber, et al.; JACS 110, 8242 (1988)
Stereoselective synthesis of the functionalized spirocyclic core of aranorosin: P. Wipf & Y. Kim; J. Org. Chem. 58, 1649 (1993)
Structure of a model for the aranorosin nucleus: R. C. Haltiwanger, et al.; Acta Cryst. C 50, 274 (1994)
Structure-activity relationships of new aranorosin analogs to antifungal activity: E.K. Vijayakumar, et al.; J. Antibiot. (Tokyo) 51, 522 (1998)
Aranorosin and a novel derivative inhibit the anti-apoptotic functions regulated by Bcl-2: T. Nakashima, et al.; BBRC 377, 1085 (2008)
Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2''): T. Suga, et al.; J. Antibiot. (Tokyo) 65, 527 (2012)