Chemical Structure
Aranorosinol B [145147-05-3]
AG-CN2-0494
Overview
- SupplierAdipoGen Life Sciences
- Product NameAranorosinol B [145147-05-3]
- Delivery Days Customer10
- CAS Number145147-05-3
- CertificationResearch Use Only
- Estimated Purity>94%
- Hazard InformationWarning
- Molecular FormulaC26H39NO7
- Molecular Weight477.6
- Scientific DescriptionAntibiotic. Moderate antibacterial and antifungal agent. Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis. - Chemical. CAS: 145147-05-3. Formula: C26H39NO7. MW: 477.6. Isolated from Phoma sp. Antibiotic. Moderate antibacterial and antifungal agent. Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis.
- SMILESCCCCCC[C@@H](C)/C=C(C)/C=C/C(N[C@@H]1C(O)O[C@]2([C@H](O3)[C@H]3C(CC(C)=O)(O)[C@H]4[C@@H]2O4)C1)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Aranorosinol A and Aranorosinol B, two new metabolites from Pseudoarachniotus roseus: production, isolation, structure elucidation and biological properties: K. Roy, et al.; J. Antibiot. 45, 1592 (1992)
- Isolation and characterization of inhibitors of the essential histidine kinase, YycG in Bacillus subtilis and Staphylococcus aureus: T. Watanabe, et al.; J. Antibiot. 56, 1045 (2003)
- Cytotoxic acyl amides from the soil fungus Gymnascella dankaliensis: L. Hammerschmidt, et al.; Bioorg. Med. Chem. 23, 712 (2015)