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Chemical Structure
Chemical Structure
Chemical Structure

Aranorosinol B [145147-05-3]

Research Use Only
AG-CN2-0494
AdipoGen Life Sciences
CAS Number145147-05-3
Product group Chemicals
Estimated Purity>94%
Molecular Weight477.6
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Aranorosinol B [145147-05-3]
  • Delivery Days Customer
    10
  • CAS Number
    145147-05-3
  • Certification
    Research Use Only
  • Estimated Purity
    >94%
  • Hazard Information
    Warning
  • Molecular Formula
    C26H39NO7
  • Molecular Weight
    477.6
  • Scientific Description
    Antibiotic. Moderate antibacterial and antifungal agent. Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis. - Chemical. CAS: 145147-05-3. Formula: C26H39NO7. MW: 477.6. Isolated from Phoma sp. Antibiotic. Moderate antibacterial and antifungal agent. Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis.
  • SMILES
    CCCCCC[C@@H](C)/C=C(C)/C=C/C(N[C@@H]1C(O)O[C@]2([C@H](O3)[C@H]3C(CC(C)=O)(O)[C@H]4[C@@H]2O4)C1)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Aranorosinol A and Aranorosinol B, two new metabolites from Pseudoarachniotus roseus: production, isolation, structure elucidation and biological properties: K. Roy, et al.; J. Antibiot. 45, 1592 (1992)
  • Isolation and characterization of inhibitors of the essential histidine kinase, YycG in Bacillus subtilis and Staphylococcus aureus: T. Watanabe, et al.; J. Antibiot. 56, 1045 (2003)
  • Cytotoxic acyl amides from the soil fungus Gymnascella dankaliensis: L. Hammerschmidt, et al.; Bioorg. Med. Chem. 23, 712 (2015)