ARD-1676 [2632305-36-1]

TargetMol Chemicals

ARD-1676 [2632305-36-1]

999

Chemical

Research Use Only

ARD-1676

C44H46ClN7O5

788.33

ARD-1676 is an orally administered androgen receptor (AR) PROTAC degrader that combines an AR ligand with a cereblon ligand. It demonstrates AR-degrading activity both in vitro and in vivo, and effectively inhibits VCaP tumor growth in mouse xenograft models [1].

3 years

C[C@H]1CC2(CN1C3=CC(Cl)=C(C#N)C=C3)CCN(CC2)C4=CC=C(C(=O)N5CCC(CN6CC=7C(C6)=CC8=C(C7)C(=O)N(C8=O)C9C(=O)NC(=O)CC9)CC5)C=C4

-20°C

12352200