Western blot analysis of extracts from LOVO cells, using RHG17 antibody.
Western blot analysis of extracts from LOVO cells, using RHG17 antibody.
ARHGAP17 Antibody
CSB-PA142309
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetARHGAP17
Overview
- SupplierCusabio
- Product NameARHGAP17 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55114
- Target nameARHGAP17
- Target descriptionRho GTPase activating protein 17
- Target synonymsMST066; MST110; MSTP038; MSTP066; MSTP110; NADRIN; neuron-associated developmentally regulated protein; PP367; PP4534; rho GTPase-activating protein 17; RhoGAP interacting with CIP4 homologs 1; rho-type GTPase-activating protein 17; RICH1; RICH-1; WBP15
- HostRabbit
- IsotypeIgG
- Protein IDQ68EM7
- Protein NameRho GTPase-activating protein 17
- Scientific DescriptionRho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1. Richnau N., J. Biol. Chem. 276:35060-35070(2001). Ota T., Nat. Genet. 36:40-45(2004). The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203