Western Blot Positive WB detected in: Hela whole cell lysate, NIH/3T3 whole cell lysate, A549 whole cell lysate, Rat lung tissue, Rat kidney tissue, Mouse heart tissue All lanes: ARHGAP18 antibody at 4.5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 75, 71 kDa Observed band size: 75 kDa
ARHGAP18 Antibody
CSB-PA850791LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetARHGAP18
Overview
- SupplierCusabio
- Product NameARHGAP18 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID93663
- Target nameARHGAP18
- Target descriptionRho GTPase activating protein 18
- Target synonymsbA307O14.2; MacGAP; rho GTPase-activating protein 18; rho-type GTPase-activating protein 18; SENEX
- HostRabbit
- IsotypeIgG
- Protein IDQ8N392
- Protein NameRho GTPase-activating protein 18
- Scientific DescriptionRho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203