ARHGDIB Polyclonal Antibody

Reddot Biotech

ARHGDIB Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ARHGDIB

Rho GDP dissociation inhibitor beta

D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; rho GDP-dissociation inhibitor 2; rho-GDI beta; RhoGDI2

Rabbit

IgG

ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them. It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.

Human, Mouse

-20°C

12352203