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ARHGEF5 Antibody, Biotin conjugated

CSB-PA618628LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetARHGEF5
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Overview

  • Supplier
    Cusabio
  • Product Name
    ARHGEF5 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID7984
  • Target name
    ARHGEF5
  • Target description
    Rho guanine nucleotide exchange factor 5
  • Target synonyms
    ephexin3; ephexin-3; GEF5; guanine nucleotide regulatory protein TIM; oncogene TIM; P60; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; rho guanine nucleotide exchange factor 5; TIM; TIM1; transforming immortalized mammary oncogene
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ12774
  • Protein Name
    Rho guanine nucleotide exchange factor 5
  • Scientific Description
    Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203