
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-5: Hela cells, Jurkat cells, 293T cells, K562 cells, mouse testis tissue, Primary antibody: CSB-PA240267(ARIH2 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
ARIH2 Antibody
CSB-PA240267
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetARIH2
Overview
- SupplierCusabio
- Product NameARIH2 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10425
- Target nameARIH2
- Target descriptionariadne RBR E3 ubiquitin protein ligase 2
- Target synonymsall-trans retinoic acid inducible RING finger; ARI2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; protein ariadne-2 homolog; RING-type E3 ubiquitin transferase ARIH2; TRIAD1
- HostRabbit
- IsotypeIgG
- Protein IDO95376
- Protein NameE3 ubiquitin-protein ligase ARIH2
- Scientific DescriptionTRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203