ART812

MedChem Express

ART812 [2607138-82-7]

5

2607138-82-7

Research Use Only

99.90

C19H16ClF4N3O4

461.79

ART812 is an orally active DNA polymerase Poltheta inhibitor with an IC50 value of 7.6 nM. ART812 has an IC50 value of 240 nM for cell based microhomology-mediated end joining (MMEJ)[1][2].

O=C([C@H]([C@H](O)[C@@H]1O)N(C2=NC(C)=CC(C(F)(F)F)=C2)C1=O)N(C3=CC=C(F)C(Cl)=C3)C

-20°C,2°C to 8°C

12352200