Artemis antibody

GeneTex

Artemis antibody

9

WB: 1:500-1:2000. IHC-P: 1:1000. ELISA: 1:10000-1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1.2 mg/ml

Unconjugated

DCLRE1C

DNA cross-link repair 1C

A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C, protein artemis, DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae), SNM1 homolog C, SNM1-like protein, severe combined immunodeficiency, type a (Athabascan)

Goat

IgG

Protein artemis

Human Artemis, a new identified 78.4 KD, novel DNA double-strand break repair/v(d)j recombination protein. This gene is located at human chromosome 10. Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5 and 3 overhang processing in non-homologous DNA end joining.

-20°C or -80°C,2°C to 8°C

12352203