Bio-Connect

AS-99 TFA

T36978
TargetMol Chemicals
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    AS-99 TFA
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    AS-99 TFA
  • Scientific Description
    AS-99 TFA is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 microM, Kd= 0.89 microM) with anti-leukemic activity. It blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1].
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200